Biomark
Apr 6, 2018

Alcohol’s Effect on Your Liver and Your Body

Moderate alcohol consumption may be beneficial to your health (thought to be protective of the heart and against stroke), but certainly the risks far outweigh the potential benefits. Besides alcohol, there are so many safer and healthier methods of protecting your heart and brain. Excessive intake of alcohol can impair the function of many organs in your body, primarily the liver. In this post, we focus on how exactly alcohol affects the liver, complications, and much more.

How Does Alcohol Affect the Liver?

The liver is an important organ with numerous functions ranging from bile production to fat metabolism. The liver also metabolizes carbohydrates, stores vitamins A, B12, D, E, and K. Furthermore, liver helps the body metabolize proteins and it filters the blood as well as performing about 500 other functions. Your health and functions of other organs and systems depend on the liver.

Alcohol intake, particularly long-term, excessive drinking, can have a negative impact on your liver and thus impairs the ability of this organ to do its job. You see, alcohol exhibits toxic effects on the liver. While it is broken down in your liver, alcohol releases various potentially harmful byproducts that damage this organ and affects the enzyme production.

Heavy drinking takes its toll on the liver in more ways than one. Here are the most common conditions that can occur due to excessive alcohol consumption:

1. Fatty Liver (Steatosis)

This is an accumulation of fat in the liver. Alcoholism and heavy drinking commonly lead to fatty liver disease. Alcohol impairs liver’s ability to metabolize fat. Then, the excess fat is stored in liver cells where it starts building up.

Symptoms of fatty liver include weight loss, decreased appetite, abdominal pain, physical weakness, confusion, fatigue and jaundice.

2. Alcoholic Hepatitis

Alcoholic hepatitis is an inflammatory condition of the liver caused by heavy alcohol intake. The disease occurs due to the direct toxic effect of alcohol in the liver, together with the toxic alcohol byproducts such as acetaldehyde (highly toxic substance and known carcinogen), fatty acid ethyl esters (FAEEs, which are also toxic to the liver and pancreas) which injure liver cells and cause inflammation.

Symptoms of alcoholic hepatitis include changes in appetite, dry mouth, weight loss, nausea and vomiting, jaundice, pain and swelling in the abdomen, fatigue and confusion.

3. Fibrosis

Fibrosis occurs when healthy tissue becomes scarred. It usually develops after a patient experienced injury or inflammation of the liver. As seen above, alcohol does induce such effects.

Signs and symptoms of liver fibrosis include loss of appetite, weight loss, fluid buildup in legs and stomach, difficulty thinking clearly and nausea.

4. Cirrhosis

Cirrhosis is the late stage of liver fibrosis. Basically, it develops as a liver’s response to damage. Chronic alcohol abuse is the most common cause of liver cirrhosis. When the liver becomes cirrhotic, it is no longer a reversible process and the complications that arise from cirrhosis are life-threatening.

Symptoms of this serious condition include bleeding and bruising easily, fatigue, itchy skin, testicular atrophy and breast enlargement in men, jaundice, abdominal fluid accumulation, nausea, loss of appetite, swelling in legs, weight loss, confusion, slurred speech, redness in palms of your hands, spider-like blood vessels in your skin.

What is Considered Heavy Drinking?

First, it’s important to define a standard drink in the United States. A standard drink is equal to 0.6oz or 14g of pure alcohol. Basically, one standard drink is equivalent to 12oz of beer, 8oz of malt liquor, 5oz of wine, and 1.5oz of “shot”. In Australia, one standard drink contains 10g of alcohol.

Binge drinking refers to intake of 5 or more drinks on a single occasion for men and 4 or more drinks per occasion for women. This usually refers to drinking that much within 2 hours.

Heavy drinking is defined as a consumption of 15 or more drinks a week for men and 8 for women.

What is the Recommended Intake of Alcohol?

If you simply can’t imagine avoiding alcohol entirely, then the best thing to do is to keep it moderate. Moderate alcohol consumption is defined as up to 1 drink a day for women and 2 drinks for men.

Other organs affected by alcohol

Alcohol affects more than just your liver. Constant drinking has a major impact on other organs too. They include:

  • Brain – alcohol intake impairs communication pathways in the brain and affects its overall function
  • Heart – long-term alcohol consumption can increase the risk of hypertension, stroke, arrhythmia (irregular heartbeat), cardiomyopathy (heart muscle stretching and drooping)
  • Kidneys – effects of alcohol on the liver can extend to kidneys. Alcohol has a diuretic effect and increases the amount of urine, but kidneys can’t keep up and are unable to regulate the flow of body fluids. This can disturb the balance of electrolytes
  • Pancreas – alcohol stimulates the pancreas to produce toxic substances that could increase the risk of pancreatitis

Tests to Monitor Alcohol Damage in the Body

If you tend to drink more alcohol than it’s recommended, you may want to consult your doctor regarding laboratory tests to monitor whether your drinking caused damage to your body. Different people can develop alcohol damage to their health even consuming less than the standard definition of heavy drinking. These tests include:

  • Vitamin B12 test – people who consume too much alcohol tend to be deficient in this vitamin, which is metabolized in the liver
  • Complete blood count (CBC) test – to detect signs of B12 or folate deficiency anemia
  • Gamma-glutamyl transferase (GGT) – a liver enzyme that is increased by heavy alcohol consumption, many other conditions that affect the liver use it too
  • Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) – liver enzymes that indicate liver damage
  • Magnesium test – low in persons who drink too much alcohol
  • Liver panel or comprehensive metabolic panel (CMP) – evaluate liver function
  • Liver fibrosis blood tests: newer generation blood tests that can accurately detect level of liver damage including steathosis (fatty), fibrosis, inflammation
  • It may be necessary to perform a liver biopsy if deemed necessary

How to Stop Drinking

While heavy drinking can be harmful to your liver and entire body, you can protect your health with wise decisions and proactive approach. Regardless of how much you drink, there’s always something you can do to lower consumption. Here are a few tips that will help you:

  • Set a realistic goal that you will not consume more than a defined number of drinks each week (it should be a much smaller amount than you usually do, of course)
  • Eat regularly and focus on a healthy diet rich in fiber; the feeling of fullness may curb cravings for alcohol
  • Identify triggers associated with your heavy drinking sessions and avoid them
  • Avoid going to places where you drink a lot
  • Don’t keep alcohol at home
  • Consider therapy to uncover underlying reasons why you drink
  • Manage stress and other problems in a healthy manner
  • Admit you have the problem and acknowledge you have the power to solve it
  • Understand why lowering (or avoiding) alcohol intake is important

Statistics

Numbers show that 15.1 million adults ages 18 or older or 6.2% of adult population in the United States had alcohol use disorder (AUD) in 2015. Of these, 9.8 million accounts for men and 5.3 million persons with AUD are women.

A WHO publication estimates that over 24% of Chinese male adults are heavy episodic drinkers.

 

Although most people tend to consider alcohol as a gateway to fun, de-stressing after work, and relaxation it can make serious harm to their liver and other organs. Alcohol consumption is a major risk factor for many life threatening diseases and cancers, and it is important to consult your doctor regarding tests that monitor liver function and degree of alcohol damage.

Don’t wait for symptoms to appear before seeking help, as blood tests very often detect liver damage long before your body tells you something is wrong. Be proactive and take the first step to better health.


Want to read our other article on fatty liver and how it affects your health? Click here!

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